A nitroglycerin tablet to treat angina is commonly administered by which route?

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Multiple Choice

A nitroglycerin tablet to treat angina is commonly administered by which route?

Sublingual administration is best because it delivers nitroglycerin into the bloodstream rapidly by absorbing through the under-tongue mucosa, bypassing the liver’s first-pass metabolism. This quick absorption produces fast relief of angina, often within minutes, which is essential for an acute episode. Swallowing the tablet (oral route) would slow onset and reduce bioavailability due to first-pass metabolism, and injections (subcutaneous or intravenous) are typically used in medical settings for controlled dosing rather than for rapid at-home relief. So placing the tablet under the tongue to dissolve allows fast, reliable relief from angina.

Sublingual administration is best because it delivers nitroglycerin into the bloodstream rapidly by absorbing through the under-tongue mucosa, bypassing the liver’s first-pass metabolism. This quick absorption produces fast relief of angina, often within minutes, which is essential for an acute episode. Swallowing the tablet (oral route) would slow onset and reduce bioavailability due to first-pass metabolism, and injections (subcutaneous or intravenous) are typically used in medical settings for controlled dosing rather than for rapid at-home relief. So placing the tablet under the tongue to dissolve allows fast, reliable relief from angina.

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